Genome-wide study predicts promoter-G4 DNA motifs regulate selective functions in bacteria: radioresistance of D. radiodurans involves G4 DNA-mediated regulation

A remarkable number of guanine-rich sequences with potential to adopt non-canonical secondary structures called G-quadruplexes (or G4 DNA) are found within gene promoters. Despite growing interest, regulatory role of quadruplex DNA motifs in intrinsic cellular function remains poorly understood. Her...

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Main Authors: Beaume, Nicolas, Pathak, Rajiv, Yadav, Vinod Kumar, Kota, Swathi, Misra, Hari S., Gautam, Hemant K., Chowdhury, Shantanu
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592403/
https://ncbi.nlm.nih.gov/pubmed/23161683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1071
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