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The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function

TRIM-NHL proteins are conserved regulators of development and differentiation but their molecular function has remained largely elusive. Here, we report an as yet unrecognized activity for the mammalian TRIM-NHL protein TRIM71 as a repressor of mRNAs. We show that TRIM71 is associated with mRNAs and...

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Détails bibliographiques
Auteurs principaux: Loedige, Inga, Gaidatzis, Dimos, Sack, Ragna, Meister, Gunter, Filipowicz, Witold
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592402/
https://ncbi.nlm.nih.gov/pubmed/23125361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1032
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