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Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors.

Amplification of the Neu/c-erbB-2 receptor tyrosine kinase has been implicated as an important event in the genesis of human breast cancer. Indeed, transgenic mice bearing either an activated form of neu or the wild-type proto-oncogene under the transcriptional control of the mouse mammary tumor vir...

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Bibliografiska uppgifter
Huvudupphovsmän: Siegel, P M, Dankort, D L, Hardy, W R, Muller, W J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC359240/
https://ncbi.nlm.nih.gov/pubmed/7935422
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