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A targeted-replacement system for identification of signals for de novo methylation in Neurospora crassa.

Transformation of eukaryotic cells can be used to test potential signals for DNA methylation. This approach is not always reliable, however, because of chromosomal position effects and because integration of multiple and/or rearranged copies of transforming DNA can influence DNA methylation. We deve...

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Main Authors: Miao, V P, Singer, M J, Rountree, M R, Selker, E U
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC359239/
https://ncbi.nlm.nih.gov/pubmed/7935421
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