Atorvastatin increases oxidative stress and modulates angiogenesis in Ossabaw swine with the metabolic syndrome

OBJECTIVE: The purpose of the present study was to evaluate the effect of atorvastatin on oxidative stress and angiogenesis in ischemic myocardium in a clinically relevant porcine model of the metabolic syndrome. METHODS: Sixteen Ossabaw pigs were fed either a high-fat diet alone or a high-fat diet...

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Main Authors: Elmadhun, Nassrene Y., Lassaletta, Antonio D., Chu, Louis M., Liu, Yuhong, Feng, Jun, Sellke, Frank W.
格式: Artigo
語言:Inglês
出版: 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592386/
https://ncbi.nlm.nih.gov/pubmed/22995723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2012.08.065
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