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Increasing phosphoproteomic coverage through sequential digestion by complementary proteases
Protein phosphorylation is a reversible post-translational modification known to regulate protein function, subcellular localization, complex formation, and protein degradation. Detailed phosphoproteomic information is critical to kinomic studies of signal transduction and for elucidation of cancer...
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Главные авторы: | , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2011
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592360/ https://ncbi.nlm.nih.gov/pubmed/22002561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-011-5466-5 |
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