Characterization of Novel Multiantigenic Vaccine Candidates with Pan-HLA Coverage against Mycobacterium tuberculosis

The low protection by the bacillus Calmette-Guérin (BCG) vaccine and existence of drug-resistant strains require better anti-Mycobacterium tuberculosis vaccines with a broad, long-lasting, antigen-specific response. Using bioinformatics tools, we identified five 19- to 40-mer signal peptide (SP) dom...

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Detalhes bibliográficos
Main Authors: Kovjazin, Riva, Shitrit, David, Preiss, Rachel, Haim, Ilanit, Triezer, Lev, Fuks, Leonardo, Nader, Abdel Rahman, Raz, Meir, Bardenstein, Ritta, Horn, Galit, Smorodinsky, Nechama I., Carmon, Lior
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592353/
https://ncbi.nlm.nih.gov/pubmed/23283639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00586-12
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