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Recombinant Vaccine Displaying the Loop-Neutralizing Determinant from Protective Antigen Completely Protects Rabbits from Experimental Inhalation Anthrax

We previously showed that a multiple antigenic peptide (MAP) vaccine displaying amino acids (aa) 304 to 319 from the 2β2-2β3 loop of protective antigen was capable of protecting rabbits from an aerosolized spore challenge with Bacillus anthracis Ames strain. Antibodies to this sequence, referred to...

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Detalhes bibliográficos
Main Authors: Oscherwitz, Jon, Yu, Fen, Jacobs, Jana L., Cease, Kemp B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592347/
https://ncbi.nlm.nih.gov/pubmed/23283638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00612-12
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