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Power and Sample Size Calculations for SNP Association Studies with Censored Time-to-Event Outcomes

For many clinical studies in cancer, germline DNA is prospectively collected for the purpose of discovering or validating Single Nucleotide Polymorphisms associated with clinical outcomes. The primary clinical endpoint for many of these studies are time-to-event outcomes such as time of death or dis...

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Detalhes bibliográficos
Main Authors: Owzar, Kouros, Li, Zhiguo, Cox, Nancy, Jung, Sin-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592339/
https://ncbi.nlm.nih.gov/pubmed/22685040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21645
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