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The Acetyl-Esterase Activity of the Hemagglutinin-Esterase Protein of Human Coronavirus OC43 Strongly Enhances the Production of Infectious Virus

Most betacoronaviruses possess an hemagglutinin-esterase (HE) protein, which appears to play a role in binding to or release from the target cell. Since this HE protein possesses an acetyl-esterase activity that removes acetyl groups from O-acetylated sialic acid, a role as a receptor-destroying enz...

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Detalhes bibliográficos
Main Authors: Desforges, Marc, Desjardins, Jessica, Zhang, Chengsheng, Talbot, Pierre J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592170/
https://ncbi.nlm.nih.gov/pubmed/23283955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02699-12
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