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Toll-Like Receptor 9 in Plasmacytoid Dendritic Cells Fails To Detect Parvoviruses

Toll-like receptor 9 (TLR9) recognizes genomes of double-stranded DNA (dsDNA) viruses in the endosome to stimulate plasmacytoid dendritic cells (pDCs). However, how and if viruses with single-stranded DNA (ssDNA) genomes are detected by pDCs remain unclear. Here we have shown that despite the abilit...

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Hlavní autoři: Mattei, Lisa M., Cotmore, Susan F., Li, Lei, Tattersall, Peter, Iwasaki, Akiko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592163/
https://ncbi.nlm.nih.gov/pubmed/23302877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03155-12
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