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Prototype Foamy Virus Protease Activity Is Essential for Intraparticle Reverse Transcription Initiation but Not Absolutely Required for Uncoating upon Host Cell Entry

Foamy viruses (FVs) are unique among retroviruses in performing genome reverse transcription (RTr) late in replication, resulting in an infectious DNA genome, and also in their unusual Pol biosynthesis and encapsidation strategy. In addition, FVs display only very limited Gag and Pol processing by t...

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Bibliografiske detaljer
Main Authors: Hütter, Sylvia, Müllers, Erik, Stanke, Nicole, Reh, Juliane, Lindemann, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592149/
https://ncbi.nlm.nih.gov/pubmed/23283957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02323-12
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