The Receptor-Binding Site of the Measles Virus Hemagglutinin Protein Itself Constitutes a Conserved Neutralizing Epitope

Here, we provide direct evidence that the receptor-binding site of measles virus (MV) hemagglutinin protein itself forms an effective conserved neutralizing epitope (CNE). Several receptor-interacting residues constitute the CNE. Thus, viral escape from neutralization has to be associated with loss...

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Détails bibliographiques
Auteurs principaux: Tahara, Maino, Ohno, Shinji, Sakai, Kouji, Ito, Yuri, Fukuhara, Hideo, Komase, Katsuhiro, Brindley, Melinda A., Rota, Paul A., Plemper, Richard K., Maenaka, Katsumi, Takeda, Makoto
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592127/
https://ncbi.nlm.nih.gov/pubmed/23283964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03029-12
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