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The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability
The transcription factor interferon regulatory factor 5 (IRF5) exerts crucial functions in the regulation of host immunity against extracellular pathogens, DNA damage-induced apoptosis, death receptor signaling, and macrophage polarization. Tight regulation of IRF5 is thus warranted for an efficient...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3592028/ https://ncbi.nlm.nih.gov/pubmed/23275442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00802-12 |
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