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The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability

The transcription factor interferon regulatory factor 5 (IRF5) exerts crucial functions in the regulation of host immunity against extracellular pathogens, DNA damage-induced apoptosis, death receptor signaling, and macrophage polarization. Tight regulation of IRF5 is thus warranted for an efficient...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Korczeniewska, Justyna, Barnes, Betsy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592028/
https://ncbi.nlm.nih.gov/pubmed/23275442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00802-12
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