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Adaptive Evolution of the Streptococcus pyogenes Regulatory Aldolase LacD.1

In the human-pathogenic bacterium Streptococcus pyogenes, the tagatose bisphosphate aldolase LacD.1 likely originated through a gene duplication event and was adapted to a role as a metabolic sensor for regulation of virulence gene transcription. Although LacD.1 retains enzymatic activity, its ances...

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Bibliografske podrobnosti
Main Authors: Cusumano, Zachary, Caparon, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592009/
https://ncbi.nlm.nih.gov/pubmed/23316044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01997-12
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