Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

Gram-negative bacteria cause approximately 70% of the infections in intensive care units. A growing number of bacterial isolates responsible for these infections are resistant to currently available antibiotics and to many in development. Most agents under development are modifications of existing d...

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Main Authors: Hernandez, Vincent, Crépin, Thibaut, Palencia, Andrés, Cusack, Stephen, Akama, Tsutomu, Baker, Stephen J., Bu, Wei, Feng, Lisa, Freund, Yvonne R., Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Mao, Weimin, Rock, Fernando L., Sexton, Holly, Sheoran, Anita, Zhang, Yanchen, Zhang, Yong-Kang, Zhou, Yasheen, Nieman, James A., Anugula, Mahipal Reddy, Keramane, El Mehdi, Savariraj, Kingsley, Reddy, D. Shekhar, Sharma, Rashmi, Subedi, Rajendra, Singh, Rajeshwar, O'Leary, Ann, Simon, Nerissa L., De Marsh, Peter L., Mushtaq, Shazad, Warner, Marina, Livermore, David M., Alley, M. R. K., Plattner, Jacob J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591879/
https://ncbi.nlm.nih.gov/pubmed/23295920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02058-12
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