Combinations of Lambda Interferon with Direct-Acting Antiviral Agents Are Highly Efficient in Suppressing Hepatitis C Virus Replication

The clinical efficacy of a pegylated form of human lambda 1 interferon (IFN-λ1; also referred to herein as lambda) has been demonstrated in patients chronically infected with hepatitis C virus (HCV) representing genotypes 1 through 4. In these proof-of-concept studies, lambda showed an improved safe...

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Bibliografiske detaljer
Main Authors: Friborg, Jacques, Levine, Steven, Chen, Chaoqun, Sheaffer, Amy K., Chaniewski, Susan, Voss, Stacey, Lemm, Julie A., McPhee, Fiona
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591875/
https://ncbi.nlm.nih.gov/pubmed/23274666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02239-12
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