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Activities of Drug Combinations against Mycobacterium tuberculosis Grown in Aerobic and Hypoxic Acidic Conditions

Mycobacterium tuberculosis is exposed to hypoxia and acidity within granulomatous lesions. In this study, an acidic culture model of M. tuberculosis was used to test drug activity against aerobic 5-day-old (A5) and hypoxic 5-, 12-, and 19-day-old (H5, H12, and H19, respectively) bacilli after 7, 14,...

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Bibliographische Detailangaben
Hauptverfasser: Piccaro, Giovanni, Giannoni, Federico, Filippini, Perla, Mustazzolu, Alessandro, Fattorini, Lanfranco
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591868/
https://ncbi.nlm.nih.gov/pubmed/23295931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02154-12
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