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Astrocytic GABA transporter GAT-1 dysfunction in experimental absence seizures

An enhanced tonic GABA(A) inhibition in the thalamus plays a crucial role in experimental absence seizures and has been attributed, on the basis of indirect evidence, to a dysfunction of the astrocytic GABA transporter-1 (GAT-1). Here, the GABA transporter current was directly investigated in thalam...

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Autores principales: Pirttimaki, Tiina, Parri, H Rheinallt, Crunelli, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591700/
https://ncbi.nlm.nih.gov/pubmed/23090943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.242016
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