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Cortical inhibition, pH and cell excitability in epilepsy: what are optimal targets for antiepileptic interventions?

Epilepsy is characterised by the propensity of the brain to generate spontaneous recurrent bursts of excessive neuronal activity, seizures. GABA-mediated inhibition is critical for restraining neuronal excitation in the brain, and therefore potentiation of GABAergic neurotransmission is commonly use...

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Detalhes bibliográficos
Main Authors: Pavlov, Ivan, Kaila, Kai, Kullmann, Dimitri M, Miles, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591695/
https://ncbi.nlm.nih.gov/pubmed/22890709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.237958
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