Monosodium Urate Activates Src/Pyk2/PI3 Kinase and Cathepsin Dependent Unconventional Protein Secretion From Human Primary Macrophages

Monosodium urate (MSU) is an endogenous danger signal that is crystallized from uric acid released from injured cells. MSU is known to activate inflammatory response in macrophages but the molecular mechanisms involved have remained uncharacterized. Activated macrophages start to secrete proteins to...

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Detaylı Bibliyografya
Asıl Yazarlar: Välimäki, Elina, Miettinen, Juho J., Lietzén, Niina, Matikainen, Sampsa, Nyman, Tuula A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591666/
https://ncbi.nlm.nih.gov/pubmed/23292187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024661
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