Identification of the Hypoxia-inducible Factor 2α Nuclear Interactome in Melanoma Cells Reveals Master Proteins Involved in Melanoma Development

Hypoxia-inducible factors (HIFs) are heterodimeric transcription factors that play a key role in cellular adaptation to hypoxia. HIF proteins are composed of an α subunit regulated by oxygen pressure (essentially HIF1α or HIF2α) and a constitutively expressed β subunit. These proteins are often over...

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Main Authors: Steunou, Anne-Lise, Ducoux-Petit, Manuelle, Lazar, Ikrame, Monsarrat, Bernard, Erard, Monique, Muller, Catherine, Clottes, Eric, Burlet-Schiltz, Odile, Nieto, Laurence
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591665/
https://ncbi.nlm.nih.gov/pubmed/23275444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.020727
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