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Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry

Chromosome region maintenance 1/exportin1/Exp1/Xpo1 (CRM1) is the major transport receptor for the export of proteins from the nucleus. It binds to nuclear export signals (NESs) that are rich in leucines and other hydrophobic amino acids. The prediction of NESs is difficult because of the extreme re...

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Main Authors: Thakar, Ketan, Karaca, Samir, Port, Sarah A., Urlaub, Henning, Kehlenbach, Ralph H.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591659/
https://ncbi.nlm.nih.gov/pubmed/23242554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024877
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