β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Chemokine receptors form a large subfamily of G protein-coupled receptors that predominantly activate heterotrimeric G(i) proteins and are involved in immune cell migration. CCX-CKR is an atypical chemokine receptor with high affinity for CCL19, CCL21, and CCL25 chemokines, but is not known to activ...

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Главные авторы: Watts, Anne O., Verkaar, Folkert, van der Lee, Miranda M. C., Timmerman, Claudia A. W., Kuijer, Martien, van Offenbeek, Jody, van Lith, Lambertus H. C. J., Smit, Martine J., Leurs, Rob, Zaman, Guido J. R., Vischer, Henry F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2013
Предметы:
Signal Transduction
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591626/
https://ncbi.nlm.nih.gov/pubmed/23341447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.406108
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