β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Chemokine receptors form a large subfamily of G protein-coupled receptors that predominantly activate heterotrimeric G(i) proteins and are involved in immune cell migration. CCX-CKR is an atypical chemokine receptor with high affinity for CCL19, CCL21, and CCL25 chemokines, but is not known to activ...

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Autors principals: Watts, Anne O., Verkaar, Folkert, van der Lee, Miranda M. C., Timmerman, Claudia A. W., Kuijer, Martien, van Offenbeek, Jody, van Lith, Lambertus H. C. J., Smit, Martine J., Leurs, Rob, Zaman, Guido J. R., Vischer, Henry F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591626/
https://ncbi.nlm.nih.gov/pubmed/23341447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.406108
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