B(0)AT2 (SLC6A15) Is Localized to Neurons and Astrocytes, and Is Involved in Mediating the Effect of Leucine in the Brain

The B(0)AT2 protein is a product of the SLC6A15 gene belonging to the SLC6 subfamily and has been shown to be a transporter of essential branched-chain amino acids. We aimed to further characterize the B(0)AT2 transporter in CNS, and to use Slc6a15 knock out (KO) mice to investigate whether B(0)AT2...

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Autores principales: Hägglund, Maria G. A., Roshanbin, Sahar, Löfqvist, Erik, Hellsten, Sofie V., Nilsson, Victor C. O., Todkar, Aniruddha, Zhu, Yinan, Stephansson, Olga, Drgonova, Jana, Uhl, George R., Schiöth, Helgi B., Fredriksson, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591439/
https://ncbi.nlm.nih.gov/pubmed/23505546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058651
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