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Inhibition of Rac and ROCK Signalling Influence Osteoblast Adhesion, Differentiation and Mineralization on Titanium Topographies

Reducing the time required for initial integration of bone-contacting implants with host tissues would be of great clinical significance. Changes in osteoblast adhesion formation and reorganization of the F-actin cytoskeleton in response to altered topography are known to be upstream of osteoblast d...

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Detalhes bibliográficos
Main Authors: Prowse, Paul D. H., Elliott, Christopher G., Hutter, Jeff, Hamilton, Douglas W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591363/
https://ncbi.nlm.nih.gov/pubmed/23505566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058898
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