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Two pathways for serum regulation of the c-fos serum response element require specific sequence elements and a minimal domain of serum response factor.

The c-fos serum response element (SRE) is necessary and sufficient for induction of the c-fos gene in response to serum and growth factors. This activation is dependent upon serum response factor (SRF), a transcriptional activator which binds the SRE. A factor, p62TCF, which binds in conjunction wit...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Johansen, F E, Prywes, R
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359118/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8065325/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.9.5920-5928.1994
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