HOXA4 Gene Promoter Hypermethylation as an Epigenetic Mechanism Mediating Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia Patients

Development of resistance to imatinib mesylate (IM) in chronic myeloid leukemia (CML) patients has emerged as a significant clinical problem. The observation that increased epigenetic silencing of potential tumor suppressor genes correlates with disease progression in some CML patients treated with...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Elias, Marjanu Hikmah, Baba, Abdul Aziz, Husin, Azlan, Sulong, Sarina, Hassan, Rosline, Sim, Goh Ai, Abdul Wahid, S. Fadilah, Ankathil, Ravindran
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3591123/
https://ncbi.nlm.nih.gov/pubmed/23484077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/129715
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk