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Transcriptional inhibition of the interleukin-8 gene by interferon is mediated by the NF-kappa B site.

The cytokine interleukin-8 (IL-8) is an important mediator of neutrophil, lymphocyte, and basophil chemotaxis and activation. Earlier we demonstrated that beta interferon (IFN-beta) can inhibit tumor necrosis factor (TNF)-induced IL-8 gene expression at the transcriptional level, apparently by a nov...

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Detalhes bibliográficos
Main Authors: Oliveira, I C, Mukaida, N, Matsushima, K, Vilcek, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC359049/
https://ncbi.nlm.nih.gov/pubmed/8035808
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