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MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5

Macroautophagy (autophagy herein) is a cellular catabolic mechanism activated in response to stress conditions including starvation, hypoxia and misfolded protein accumulation. Abnormalities in autophagy were associated with pathologies including cancer and neurodegenerative diseases. Hence, elucida...

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Bibliografiske detaljer
Main Authors: Tekirdag, Kumsal Ayse, Korkmaz, Gozde, Ozturk, Deniz Gulfem, Agami, Reuven, Gozuacik, Devrim
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590257/
https://ncbi.nlm.nih.gov/pubmed/23322078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23117
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