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Functional differences between HOX proteins conferred by two residues in the homeodomain N-terminal arm.

Hox genes encode homeodomain-containing transcriptional regulators that function during development to specify positional identity along embryonic axes. The homeodomain is composed of a flexible N-terminal arm and three alpha helices, and it differentially binds DNA. A number of homeodomains recogni...

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Bibliografiska uppgifter
Huvudupphovsmän: Phelan, M L, Sadoul, R, Featherstone, M S
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1994
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC359025/
https://ncbi.nlm.nih.gov/pubmed/7913516
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