The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

Effector functions of inflammatory IL-17–producing Th (Th17) cells have been linked to autoimmune diseases such as experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). However, what determines Th17 cell encephalitogenicity is still unresolved. Here, we show that...

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Detalhes bibliográficos
Main Authors: Brüstle, Anne, Brenner, Dirk, Knobbe, Christiane B., Lang, Philipp A., Virtanen, Carl, Hershenfield, Brian M., Reardon, Colin, Lacher, Sonja M., Ruland, Jürgen, Ohashi, Pamela S., Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590210/
https://ncbi.nlm.nih.gov/pubmed/23114599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63528
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