The Expression and Activity of Cathepsins D, H and K in Asthmatic Airways

Tumstatin is an anti-angiogenic collagen IV α3 fragment, levels of which are reduced in the airways of asthmatics. Its reduction may be due to the degradation by extracellular matrix (ECM) proteases. Cathepsins play a role in ECM remodelling, with cathepsin D, H and K (CTSD, CTSH and CTSK) being ass...

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Bibliographic Details
Main Authors: Faiz, Alen, Tjin, Gavin, Harkness, Louise, Weckmann, Markus, Bao, Shisan, Black, Judith L., Oliver, Brian G. G., Burgess, Janette K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590183/
https://ncbi.nlm.nih.gov/pubmed/23483898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057245
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