Apical CFTR Expression in Human Nasal Epithelium Correlates with Lung Disease in Cystic Fibrosis

INTRODUCTION: Although most individuals with cystic fibrosis (CF) develop progressive obstructive lung disease, disease severity is highly variable, even for individuals with similar CFTR mutations. Measurements of chloride transport as expression of CFTR function in nasal epithelial cells correlate...

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Main Authors: van Meegen, Marit Arianne, Terheggen-Lagro, Suzanne Willemina Julia, Koymans, Kirsten Judith, van der Ent, Cornelis Korstiaan, Beekman, Jeffrey Matthijn
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590182/
https://ncbi.nlm.nih.gov/pubmed/23483918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057617
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