Cardiomyocyte-Specific Deletion of Endothelin Receptor A Rescues Ageing-Associated Cardiac Hypertrophy and Contractile Dysfunction: Role of Autophagy

Cardiac ageing is manifested as cardiac remodeling and contractile dysfunction although precise mechanisms remain elusive. This study was designed to examine the role of endothelin-1 (ET-1) in ageing-associated myocardial morphological and contractile defects. Echocardiographic and cardiomyocyte con...

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Autores principales: Ceylan-Isik, Asli F., Dong, Maolong, Zhang, Yingmei, Dong, Feng, Turdi, Subat, Nair, Sreejayan, Yanagisawa, Masashi, Ren, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590116/
https://ncbi.nlm.nih.gov/pubmed/23381122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-013-0335-3
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