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Nkx1-2 is a transcriptional repressor and is essential for the activation of Brachyury in P19 mouse embryonal carcinoma cell

Activation of Wnt/β-catenin signaling is crucial for the differentiation of pluripotent stem cells, namely the epiblast, embryonic stem, and embryonal carcinoma cells, into mesendoderm. However, downstream events of Wnt/β-catenin signaling that control the formation of mesendoderm are still unclear....

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Autori principali: Tamashiro, Dana Ann A., Alarcon, Vernadeth B., Marikawa, Yusuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590073/
https://ncbi.nlm.nih.gov/pubmed/22475651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diff.2012.02.010
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