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Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase.

Cyclins are pivotal in the coordinate regulation of the cell cycle. By physical association, they are able to activate at least one of the cyclin-dependent kinases, cdc2. How this association between the catalytic moiety and cyclins leads to subsequent activation of the kinase remains unclear. In th...

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Publicado en:Mol Cell Biol
Autores principales: Lees, E M, Harlow, E
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1993
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.2.1194-1201.1993
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