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Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase.

Cyclins are pivotal in the coordinate regulation of the cell cycle. By physical association, they are able to activate at least one of the cyclin-dependent kinases, cdc2. How this association between the catalytic moiety and cyclins leads to subsequent activation of the kinase remains unclear. In th...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Lees, E M, Harlow, E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.2.1194
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