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Noradrenergic Enhancement of Reconsolidation in the Amygdala Impairs Extinction of Conditioned Fear in Rats – a Possible Mechanism for the Persistence of Traumatic Memories in PTSD

BACKGROUND: Post-traumatic stress disorder (PTSD) is associated with enhanced noradrenergic activity. Animal and human studies demonstrate that noradrenergic stimulation augments consolidation of fear learning. Retrieval of well-established memories by presenting a learned fear cue triggers reconsol...

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Bibliografiska uppgifter
Huvudupphovsmän: Dębiec, Jacek, Bush, David E. A., LeDoux, Joseph E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590026/
https://ncbi.nlm.nih.gov/pubmed/21394851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/da.20803
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