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Association Between Promoter Polymorphisms of the GRP78 Gene and Risk of Type 2 Diabetes in a Chinese Han Population

There are large amounts of unfolding or misfolding protein accumulation in the endoplasmic reticulum in patients with type 2 diabetes (T2D), which in turn induces the expression of the glucose-regulated protein 78 (GRP78) that plays a key role in influencing insulin secretion and maintaining glucose...

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書誌詳細
主要な著者: Liu, Shengyuan, Li, Keshen, Li, Tao, Xiong, Xingdong, Yao, Songpo, Chen, Zhongwei, Wang, Changyi, Zhao, Bin
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589892/
https://ncbi.nlm.nih.gov/pubmed/23402331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1909
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