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In vitro oxidative inactivation of human presequence protease (hPreP)

The mitochondrial peptidasome called presequence protease (PreP) is responsible for the degradation of presequences and other unstructured peptides including the amyloid-β peptide, whose accumulation may have deleterious effects on mitochondrial function. Recent studies showed that PreP activity is...

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Bibliographic Details
Main Authors: Teixeira, Pedro Filipe, Pinho, Catarina Moreira, Branca, Rui M., Lehtiö, Janne, Levine, Rodney L., Glaser, Elzbieta
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589710/
https://ncbi.nlm.nih.gov/pubmed/23041349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.09.039
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