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PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties

Background: Non-synonymous single-nucleotide polymorphisms (nsSNPs) within the coding regions of genes causing amino acid substitutions (AASs) may have a large impact on protein function. The possibilities to identify nsSNPs across genomes have increased notably with the advent of next-generation se...

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Main Authors: Li, Xidan, Kierczak, Marcin, Shen, Xia, Ahsan, Muhammad, Carlborg, Örjan, Marklund, Stefan
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589708/
https://ncbi.nlm.nih.gov/pubmed/23508070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00021
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