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PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties

Background: Non-synonymous single-nucleotide polymorphisms (nsSNPs) within the coding regions of genes causing amino acid substitutions (AASs) may have a large impact on protein function. The possibilities to identify nsSNPs across genomes have increased notably with the advent of next-generation se...

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Hlavní autoři: Li, Xidan, Kierczak, Marcin, Shen, Xia, Ahsan, Muhammad, Carlborg, Örjan, Marklund, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589708/
https://ncbi.nlm.nih.gov/pubmed/23508070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00021
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