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PASE: a novel method for functional prediction of amino acid substitutions based on physicochemical properties
Background: Non-synonymous single-nucleotide polymorphisms (nsSNPs) within the coding regions of genes causing amino acid substitutions (AASs) may have a large impact on protein function. The possibilities to identify nsSNPs across genomes have increased notably with the advent of next-generation se...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589708/ https://ncbi.nlm.nih.gov/pubmed/23508070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00021 |
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