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Tolerogenic and Activatory Plasmacytoid Dendritic Cells in Autoimmunity

Plasmacytoid dendritic cells (pDCs) are a particular subset of DCs that link innate and adaptive immunity. They are responsible for the substantial production of type 1 interferon (IFN-I) in response to viral RNA or DNA through activation of TLR7 and 9. Furthermore, pDCs present antigens (Ag) and in...

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Autori principali: Guéry, Leslie, Hugues, Stéphanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589693/
https://ncbi.nlm.nih.gov/pubmed/23508732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00059
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