The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase.

As part of its trophic action to maintain the steroidogenic capacity of adrenocortical cells, corticotropin (ACTH) increases the transcription of the cytochrome P-450 steroid hydroxylase genes, including the gene encoding steroid 21-hydroxylase (21-OHase). We previously identified several promoter e...

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Bibliographic Details
Main Authors: Wilson, T E, Mouw, A R, Weaver, C A, Milbrandt, J, Parker, K L
Format: Artigo
Language:Inglês
Published: 1993
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC358969/
https://ncbi.nlm.nih.gov/pubmed/8380897
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