NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through eNOS Activation

BACKGROUND: Reactive Oxygen Species (ROS) serve signaling functions in the vasculature, and hypoxia has been associated with increased ROS production. NADPH oxidase 4 (Nox4) is an ROS-producing enzyme that is highly expressed in the endothelium, yet its specific role is unknown. We sought to determi...

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Hlavní autoři: Craige, Siobhan M., Kai, Chen, Pei, Yongmei, Chunying, Li, Xiaoyun, Huang, Christine, Chen, Shibata, Rei, Sato, Kaori, Walsh, Kenneth, Keaney, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589548/
https://ncbi.nlm.nih.gov/pubmed/21788590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.030775
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