SMALL MOLECULE INHIBITORS OF STAT3 PROTECT AGAINST ANGIOTENSIN II-INDUCED VASCULAR DYSFUNCTION AND HYPERTENSION

Angiotensin II (Ang II) is known to promote vascular disease and hypertension in part by formation of cytokines like interleukin-6 (IL-6). However, the role of signal transducer and activator of transcription 3 (STAT3) in these process and Ang II/IL-6 signaling is unclear. Using two models, we teste...

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Hauptverfasser: Johnson, Andrew W., Kinzenbaw, Dale A., Modrick, Mary L., Faraci, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589547/
https://ncbi.nlm.nih.gov/pubmed/23266544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.00299
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