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Geographical Distribution of MTHFR C677T, A1298C and MTRR A66G Gene Polymorphisms in China: Findings from 15357 Adults of Han Nationality

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) C677T, A1298C and methionine synthase reductase (MTRR) A66G polymorphisms are important genetic determinants for homocysteine (Hcy) levels, and are associated with several disorders. These polymorphisms are heterogeneously distributed worldwide...

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Detalhes bibliográficos
Main Authors: Yang, Boyi, Liu, Yuyan, Li, Yongfang, Fan, Shujun, Zhi, Xueyuan, Lu, Xiangxiang, Wang, Da, Zheng, Quanmei, Wang, Yinuo, Wang, Yanxun, Sun, Guifan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589470/
https://ncbi.nlm.nih.gov/pubmed/23472119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057917
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