Cross-coupling of signal transduction pathways: the dioxin receptor mediates induction of cytochrome P-450IA1 expression via a protein kinase C-dependent mechanism.

Signal transduction by dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) is mediated by the intracellular dioxin receptor which, in its dioxin-activated state, regulates transcription of target genes encoding drug-metabolizing enzymes, such as cytochrome P-450IA1 and glutathione S-transferase Ya. Exposur...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Berghard, A, Gradin, K, Pongratz, I, Whitelaw, M, Poellinger, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8380231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.1.677-689.1993
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